Publications

List updated May. 2025

1. Ruffel S, Del Rosario J, Lacombe B, Rouached H, Gutiérrez RA, Coruzzi GM, Krouk G. *Nitrate Sensing and Signaling in Plants: Comparative Insights and Nutritional Interactions*. **Annu Rev Plant Biol.** 2025 May;76(1):25-52. doi: 10.1146/annurev-arplant-083123-053039. PMID: 40393732. [here](https://doi.org/10.1146/annurev-arplant-083123-053039)

2. Carré C, Carluer JB, Chaux C, Estoup-Streiff C, Roche N, Hosy E, Mas A, Krouk G. *Next-Gen GWAS: full 2D epistatic interaction maps retrieve part of missing heritability and improve phenotypic prediction*. **Genome Biol.** 2024 Mar 25;25(1):76. doi: 10.1186/s13059-024-03202-0. PMID: 38523316; PMCID: PMC10962106. [here](https://doi.org/10.1186/s13059-024-03202-0)

3. Shanks CM, Rothkegel K, Brooks MD, Cheng CY, Alvarez JM, Ruffel S, Krouk G, Gutiérrez RA, Coruzzi GM. *Nitrogen sensing and regulatory networks: it's about time and space*. **Plant Cell.** 2024 May 1;36(5):1482-1503. doi: 10.1093/plcell/koae038. PMID: 38366121; PMCID: PMC11062454. [here](https://doi.org/10.1093/plcell/koae038)

4. DeLoose M, Clúa J, Cho H, Zheng L, Masmoudi K, Desnos T, Krouk G, Nussaume L, Poirier Y, Rouached H. *Recent advances in unraveling the mystery of combined nutrient stress in plants*. **Plant J.** 2024 Mar;117(6):1764-1780. doi: 10.1111/tpj.16511. Epub 2023 Nov 3. PMID: 37921230. [here](https://doi.org/10.1111/tpj.16511)

5. Crabos A, Huang Y, Boursat T, Maurel C, Ruffel S, Krouk G, Boursiac Y. *Distinct early transcriptional regulations by turgor and osmotic potential in the roots of Arabidopsis*. **J Exp Bot.** 2023 Sep 29;74(18):5917-5930. doi: 10.1093/jxb/erad307. PMID: 37603421. [here](https://doi.org/10.1093/jxb/erad307)

6. Nguyen NN, Lamotte O, Alsulaiman M, Ruffel S, Krouk G, Berger N, Demolombe V, Nespoulous C, Dang TMN, Aimé S, Berthomieu P, Dubos C, Wendehenne D, Vile D, Gosti F. *Reduction in PLANT DEFENSIN 1 expression in Arabidopsis thaliana results in increased resistance to pathogens and zinc toxicity*. **J Exp Bot.** 2023 Sep 13;74(17):5374-5393. doi: 10.1093/jxb/erad228. PMID: 37326591. [here](https://doi.org/10.1093/jxb/erad228)

7. Krouk G, Szponarski W, Ruffel S. *Unleashing the potential of peptides in agriculture and beyond*. **Trends Plant Sci.** 2023 Jul;28(7):734-736. doi: 10.1016/j.tplants.2023.03.025. Epub 2023 Apr 15. PMID: 37069001. [here](https://doi.org/10.1016/j.tplants.2023.03.025)

8. Cho H, Banf M, Shahzad Z, Van Leene J, Bossi F, Ruffel S, Bouain N, Cao P, Krouk G, De Jaeger G, Lacombe B, Brandizzi F, Rhee SY, Rouached H. *ARSK1 activates TORC1 signaling to adjust growth to phosphate availability in Arabidopsis*. **Curr Biol.** 2023 May 8;33(9):1778-1786.e5. doi: 10.1016/j.cub.2023.03.005. Epub 2023 Mar 23. PMID: 36963384; PMCID: PMC10175222. [here](https://doi.org/10.1016/j.cub.2023.03.005)

9. Courrèges-Clercq J, Krouk G. *Two nitrate sensors, how many more? Nat Plants*. **2022 Nov;8(11):1212-1213.** doi: 10.1038/s41477-022-01276-x. PMID: 36333589. [here](https://doi.org/10.1038/s41477-022-01276-x)

10. Brooks MD, Reed KM, Krouk G, Coruzzi GM, Bargmann BOR. *The TARGET System: Rapid Identification of Direct Targets of Transcription Factors by Gene Regulation in Plant Cells*. **Methods Mol Biol.** 2023;2594:1-12. doi: 10.1007/978-1-0716-2815-7_1. PMID: 36264484. [here](https://doi.org/10.1007/978-1-0716-2815-7_1)

11. Berger N, Demolombe V, Hem S, Rofidal V, Steinmann L, Krouk G, Crabos A, Nacry P, Verdoucq L, Santoni V. *Root Membrane Ubiquitinome under Short-Term Osmotic Stress*. **Int J Mol Sci.** 2022 Feb 10;23(4):1956. doi: 10.3390/ijms23041956. PMID: 35216074; PMCID: PMC8879470. [here](https://doi.org/10.3390/ijms23041956)

12. Liu Y, Maniero RA, Giehl RFH, Melzer M, Steensma P, Krouk G, Fitzpatrick TB, von Wirén N. *PDX1.1-dependent biosynthesis of vitamin B₆ protects roots from ammonium-induced oxidative stress*. **Mol Plant.** 2022 May 2;15(5):820-839. doi: 10.1016/j.molp.2022.01.012. Epub 2022 Jan 19. PMID: 35063660. [here](https://doi.org/10.1016/j.molp.2022.01.012)

13. Camut L, Gallova B, Jilli L, Sirlin-Josserand M, Carrera E, Sakvarelidze- Achard L, Ruffel S, Krouk G, Thomas SG, Hedden P, Phillips AL, Davière JM, Achard P. *Nitrate signaling promotes plant growth by upregulating gibberellin biosynthesis and destabilization of DELLA proteins*. **Curr Biol.** 2021 Nov 22;31(22):4971-4982.e4. doi: 10.1016/j.cub.2021.09.024. Epub 2021 Oct 5. PMID: 34614391. [here](https://doi.org/10.1016/j.cub.2021.09.024)

14. Safi A, Medici A, Szponarski W, Martin F, Clément-Vidal A, Marshall-Colon A, Ruffel S, Gaymard F, Rouached H, Leclercq J, Coruzzi G, Lacombe B, Krouk G. *GARP transcription factors repress Arabidopsis nitrogen starvation response via ROS- dependent and -independent pathways*. **J Exp Bot.** 2021 May 4;72(10):3881-3901. doi: 10.1093/jxb/erab114. PMID: 33758916; PMCID: PMC8096604. [here](https://doi.org/10.1093/jxb/erab114)

15. Krouk G, Kiba T. *Nitrogen and Phosphorus interactions in plants: from agronomic to physiological and molecular insights*. **Curr Opin Plant Biol.** 2020 Oct;57:104-109. doi: 10.1016/j.pbi.2020.07.002. Epub 2020 Sep 1. PMID: 32882570. [here](https://doi.org/10.1016/j.pbi.2020.07.002)

16. Parry G, Provart NJ, Brady SM, Uzilday B; Multinational Arabidopsis Steering Committee. *Current status of the multinational Arabidopsis community*. **Plant Direct.** 2020 Aug 2;4(7):e00248. doi: 10.1002/pld3.248. PMID: 32775952; PMCID: PMC7396448. [here](https://doi.org/10.1002/pld3.248)

17. Maghiaoui A, Bouguyon E, Cuesta C, Perrine-Walker F, Alcon C, Krouk G, Benková E, Nacry P, Gojon A, Bach L. *The Arabidopsis NRT1.1 transceptor coordinately controls auxin biosynthesis and transport to regulate root branching in response to nitrate*. **J Exp Bot.** 2020 Jul 25;71(15):4480-4494. doi: 10.1093/jxb/eraa242. PMID: 32428238. [here](https://doi.org/10.1093/jxb/eraa242)

18. Vidal EA, Alvarez JM, Araus V, Riveras E, Brooks MD, Krouk G, Ruffel S, Lejay L, Crawford NM, Coruzzi GM, Gutiérrez RA. *Nitrate in 2020: Thirty Years from Transport to Signaling Networks*. **Plant Cell.** 2020 Jul;32(7):2094-2119. doi: 10.1105/tpc.19.00748. Epub 2020 Mar 13. Erratum in: Plant Cell. 2024 Oct 22:koae265. doi: 10.1093/plcell/koae265. PMID: 32169959; PMCID: PMC7346567. [here](https://doi.org/10.1105/tpc.19.00748)

19. Alvarez JM, Schinke AL, Brooks MD, Pasquino A, Leonelli L, Varala K, Safi A, Krouk G, Krapp A, Coruzzi GM. *Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade*. **Nat Commun.** 2020 Mar 2;11(1):1157. doi: 10.1038/s41467-020-14979-6. PMID: 32123177; PMCID: PMC7052136. [here](https://doi.org/10.1038/s41467-020-14979-6)

20. Falter-Braun P, Brady S, Gutiérrez RA, Coruzzi GM, Krouk G. *iPlant Systems Biology (iPSB): An International Network Hub in the Plant Community*. **Mol Plant.** 2019 Jun 3;12(6):727-730. doi: 10.1016/j.molp.2019.05.005. Epub 2019 May 21. PMID: 31125688. [here](https://doi.org/10.1016/j.molp.2019.05.005)

21. Bouain N, Krouk G, Lacombe B, Rouached H. *Getting to the Root of Plant Mineral Nutrition: Combinatorial Nutrient Stresses Reveal Emergent Properties*. **Trends Plant Sci.** 2019 Jun;24(6):542-552. doi: 10.1016/j.tplants.2019.03.008. Epub 2019 Apr 18. PMID: 31006547. [here](https://doi.org/10.1016/j.tplants.2019.03.008)

22. Brooks MD, Cirrone J, Pasquino AV, Alvarez JM, Swift J, Mittal S, Juang CL, Varala K, Gutiérrez RA, Krouk G, Shasha D, Coruzzi GM. *Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions*. **Nat Commun.** 2019 Apr 5;10(1):1569. doi: 10.1038/s41467-019-09522-1. PMID: 30952851; PMCID: PMC6451032. [here](https://doi.org/10.1038/s41467-019-09522-1)

23. Medici A, Szponarski W, Dangeville P, Safi A, Dissanayake IM, Saenchai C, Emanuel A, Rubio V, Lacombe B, Ruffel S, Tanurdzic M, Rouached H, Krouk G. *Identification of Molecular Integrators Shows that Nitrogen Actively Controls the Phosphate Starvation Response in Plants*. **Plant Cell.** 2019 May;31(5):1171-1184. doi: 10.1105/tpc.18.00656. Epub 2019 Mar 14. PMID: 30872321; PMCID: PMC6533016. [here](https://doi.org/10.1105/tpc.18.00656)

24. Bellegarde F, Maghiaoui A, Boucherez J, Krouk G, Lejay L, Bach L, Gojon A, Martin A. *The Chromatin Factor HNI9 and ELONGATED HYPOCOTYL5 Maintain ROS Homeostasis under High Nitrogen Provision*. **Plant Physiol.** 2019 May;180(1):582-592. doi: 10.1104/pp.18.01473. Epub 2019 Mar 1. PMID: 30824566; PMCID: PMC6501088. [here](https://doi.org/10.1104/pp.18.01473)

25. Poitout A, Crabos A, Petřík I, Novák O, Krouk G, Lacombe B, Ruffel S. *Responses to Systemic Nitrogen Signaling in Arabidopsis Roots Involve <i>trans</i>-Zeatin in Shoots*. **Plant Cell.** 2018 Jun;30(6):1243-1257. doi: 10.1105/tpc.18.00011. Epub 2018 May 15. PMID: 29764985; PMCID: PMC6048791. [here](https://doi.org/10.1105/tpc.18.00011)

26. Kisko M, Bouain N, Safi A, Medici A, Akkers RC, Secco D, Fouret G, Krouk G, Aarts MG, Busch W, Rouached H. *<i>LPCAT1</i> controls phosphate homeostasis in a zinc-dependent manner*. **Elife.** 2018 Feb 17;7:e32077. doi: 10.7554/eLife.32077. PMID: 29453864; PMCID: PMC5826268. [here](https://doi.org/10.7554/eLife.32077)

27. Friesner J, Assmann SM, Bastow R, Bailey-Serres J, Beynon J, Brendel V, Buell CR, Bucksch A, Busch W, Demura T, Dinneny JR, Doherty CJ, Eveland AL, Falter-Braun P, Gehan MA, Gonzales M, Grotewold E, Gutierrez R, Kramer U, Krouk G, Ma S, Markelz RJC, Megraw M, Meyers BC, Murray JAH, Provart NJ, Rhee S, Smith R, Spalding EP, Taylor C, Teal TK, Torii KU, Town C, Vaughn M, Vierstra R, Ware D, Wilkins O, Williams C, Brady SM. *The Next Generation of Training for Arabidopsis Researchers: Bioinformatics and Quantitative Biology*. **Plant Physiol.** 2017 Dec;175(4):1499-1509. doi: 10.1104/pp.17.01490. PMID: 29208732; PMCID: PMC5717721. [here](https://doi.org/10.1104/pp.17.01490)

28. Pal S, Kisko M, Dubos C, Lacombe B, Berthomieu P, Krouk G, Rouached H. *TransDetect Identifies a New Regulatory Module Controlling Phosphate Accumulation*. **Plant Physiol.** 2017 Oct;175(2):916-926. doi: 10.1104/pp.17.00568. Epub 2017 Aug 21. PMID: 28827455; PMCID: PMC5619893. [here](https://doi.org/10.1104/pp.17.00568)

29. Safi A, Medici A, Szponarski W, Ruffel S, Lacombe B, Krouk G. *The world according to GARP transcription factors*. **Curr Opin Plant Biol.** 2017 Oct;39:159-167. doi: 10.1016/j.pbi.2017.07.006. Epub 2017 Aug 10. PMID: 28802165. [here](https://doi.org/10.1016/j.pbi.2017.07.006)

30. Carré C, Mas A, Krouk G. *Reverse engineering highlights potential principles of large gene regulatory network design and learning*. **NPJ Syst Biol Appl.** 2017 Jun 22;3:17. doi: 10.1038/s41540-017-0019-y. PMID: 28649444; PMCID: PMC5481436. [here](https://doi.org/10.1038/s41540-017-0019-y)

31. Krouk G. *Nitrate signalling: Calcium bridges the nitrate gap*. **Nat Plants.** 2017 Jun 19;3:17095. doi: 10.1038/nplants.2017.95. PMID: 28628086. [here](https://doi.org/10.1038/nplants.2017.95)

32. Ristova D, Carré C, Pervent M, Medici A, Kim GJ, Scalia D, Ruffel S, Birnbaum KD, Lacombe B, Busch W, Coruzzi GM, Krouk G. *Combinatorial interaction network of transcriptomic and phenotypic responses to nitrogen and hormones in the Arabidopsis thaliana root*. **Sci Signal.** 2016 Oct 25;9(451):rs13. doi: 10.1126/scisignal.aaf2768. PMID: 27811143. [here](https://doi.org/10.1126/scisignal.aaf2768)

33. Bellati J, Champeyroux C, Hem S, Rofidal V, Krouk G, Maurel C, Santoni V. *Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics*. **Mol Cell Proteomics.** 2016 Nov;15(11):3473-3487. doi: 10.1074/mcp.M116.060087. Epub 2016 Sep 8. PMID: 27609422; PMCID: PMC5098044. [here](https://doi.org/10.1074/mcp.M116.060087)

34. Bouguyon E, Perrine-Walker F, Pervent M, Rochette J, Cuesta C, Benkova E, Martinière A, Bach L, Krouk G, Gojon A, Nacry P. *Nitrate Controls Root Development through Posttranscriptional Regulation of the NRT1.1/NPF6.3 Transporter/Sensor*. **Plant Physiol.** 2016 Oct;172(2):1237-1248. doi: 10.1104/pp.16.01047. Epub 2016 Aug 19. PMID: 27543115; PMCID: PMC5047109. [here](https://doi.org/10.1104/pp.16.01047)

35. O'Brien JA, Vega A, Bouguyon E, Krouk G, Gojon A, Coruzzi G, Gutiérrez RA. *Nitrate Transport, Sensing, and Responses in Plants*. **Mol Plant.** 2016 Jun 6;9(6):837-56. doi: 10.1016/j.molp.2016.05.004. Epub 2016 May 19. PMID: 27212387. [here](https://doi.org/10.1016/j.molp.2016.05.004)

36. Krouk G. *Hormones and nitrate: a two-way connection*. **Plant Mol Biol.** 2016 Aug;91(6):599-606. doi: 10.1007/s11103-016-0463-x. Epub 2016 Mar 22. PMID: 27003907. [here](https://doi.org/10.1007/s11103-016-0463-x)

37. Ruffel S, Poitout A, Krouk G, Coruzzi GM, Lacombe B. *Long-distance nitrate signaling displays cytokinin dependent and independent branches*. **J Integr Plant Biol.** 2016 Mar;58(3):226-9. doi: 10.1111/jipb.12453. Epub 2016 Feb 23. PMID: 26619818. [here](https://doi.org/10.1111/jipb.12453)

38. Medici A, Marshall-Colon A, Ronzier E, Szponarski W, Wang R, Gojon A, Crawford NM, Ruffel S, Coruzzi GM, Krouk G. *AtNIGT1/HRS1 integrates nitrate and phosphate signals at the Arabidopsis root tip*. **Nat Commun.** 2015 Feb 27;6:6274. doi: 10.1038/ncomms7274. PMID: 25723764; PMCID: PMC4373655. [here](https://doi.org/10.1038/ncomms7274)

39. Krouk G, Carré C, Fizames C, Gojon A, Ruffel S, Lacombe B. *GeneCloud Reveals Semantic Enrichment in Lists of Gene Descriptions*. **Mol Plant.** 2015 Jun;8(6):971-3. doi: 10.1016/j.molp.2015.02.005. Epub 2015 Feb 21. PMID: 25707756. [here](https://doi.org/10.1016/j.molp.2015.02.005)

40. Bouguyon E, Brun F, Meynard D, Kubeš M, Pervent M, Leran S, Lacombe B, Krouk G, Guiderdoni E, Zažímalová E, Hoyerová K, Nacry P, Gojon A. *Multiple mechanisms of nitrate sensing by Arabidopsis nitrate transceptor NRT1.1*. **Nat Plants.** 2015 Mar 2;1:15015. doi: 10.1038/nplants.2015.15. PMID: 27246882. [here](https://doi.org/10.1038/nplants.2015.15)

41. Li Y, Krouk G, Coruzzi GM, Ruffel S. *Finding a nitrogen niche: a systems integration of local and systemic nitrogen signalling in plants*. **J Exp Bot.** 2014 Oct;65(19):5601-10. doi: 10.1093/jxb/eru263. Epub 2014 Jun 24. PMID: 24963003. [here](https://doi.org/10.1093/jxb/eru263)

42. Para A, Li Y, Marshall-Colón A, Varala K, Francoeur NJ, Moran TM, Edwards MB, Hackley C, Bargmann BO, Birnbaum KD, McCombie WR, Krouk G, Coruzzi GM. *Hit- and-run transcriptional control by bZIP1 mediates rapid nutrient signaling in Arabidopsis*. **Proc Natl Acad Sci U S A.** 2014 Jul 15;111(28):10371-6. doi: 10.1073/pnas.1404657111. Epub 2014 Jun 23. PMID: 24958886; PMCID: PMC4104873. [here](https://doi.org/10.1073/pnas.1404657111)

43. Medici A, Krouk G. *The primary nitrate response: a multifaceted signalling pathway*. **J Exp Bot.** 2014 Oct;65(19):5567-76. doi: 10.1093/jxb/eru245. Epub 2014 Jun 18. PMID: 24942915. [here](https://doi.org/10.1093/jxb/eru245)

44. Vidal EA, Moyano TC, Krouk G, Katari MS, Tanurdzic M, McCombie WR, Coruzzi GM, Gutiérrez RA. *Integrated RNA-seq and sRNA-seq analysis identifies novel nitrate-responsive genes in Arabidopsis thaliana roots*. **BMC Genomics.** 2013 Oct 11;14:701. doi: 10.1186/1471-2164-14-701. PMID: 24119003; PMCID: PMC3906980. [here](https://doi.org/10.1186/1471-2164-14-701)

45. Bargmann BO, Vanneste S, Krouk G, Nawy T, Efroni I, Shani E, Choe G, Friml J, Bergmann DC, Estelle M, Birnbaum KD. *A map of cell type-specific auxin responses*. **Mol Syst Biol.** 2013;9:688. doi: 10.1038/msb.2013.40. PMID: 24022006; PMCID: PMC3792342. [here](https://doi.org/10.1038/msb.2013.40)

46. Rosas U, Cibrian-Jaramillo A, Ristova D, Banta JA, Gifford ML, Fan AH, Zhou RW, Kim GJ, Krouk G, Birnbaum KD, Purugganan MD, Coruzzi GM. *Integration of responses within and across Arabidopsis natural accessions uncovers loci controlling root systems architecture*. **Proc Natl Acad Sci U S A.** 2013 Sep 10;110(37):15133-8. doi: 10.1073/pnas.1305883110. Epub 2013 Aug 26. Erratum in: Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2555. doi: 10.1073/pnas.1507065112. PMID: 23980140; PMCID: PMC3773737. [here](https://doi.org/10.1073/pnas.1305883110)

47. Krouk G, Lingeman J, Colon AM, Coruzzi G, Shasha D. *Gene regulatory networks in plants: learning causality from time and perturbation*. **Genome Biol.** 2013 Jun 27;14(6):123. doi: 10.1186/gb-2013-14-6-123. PMID: 23805876; PMCID: PMC3707030. [here](https://doi.org/10.1186/gb-2013-14-6-123)

48. Boursiac Y, Léran S, Corratgé-Faillie C, Gojon A, Krouk G, Lacombe B. *ABA transport and transporters*. **Trends Plant Sci.** 2013 Jun;18(6):325-33. doi: 10.1016/j.tplants.2013.01.007. Epub 2013 Mar 1. PMID: 23453706. [here](https://doi.org/10.1016/j.tplants.2013.01.007)

49. Bargmann BO, Marshall-Colon A, Efroni I, Ruffel S, Birnbaum KD, Coruzzi GM, Krouk G. *TARGET: a transient transformation system for genome-wide transcription factor target discovery*. **Mol Plant.** 2013 May;6(3):978-80. doi: 10.1093/mp/sst010. Epub 2013 Jan 18. PMID: 23335732; PMCID: PMC3660954. [here](https://doi.org/10.1093/mp/sst010)

50. Ristova D, Rosas U, Krouk G, Ruffel S, Birnbaum KD, Coruzzi GM. *RootScape: a landmark-based system for rapid screening of root architecture in Arabidopsis*. **Plant Physiol.** 2013 Mar;161(3):1086-96. doi: 10.1104/pp.112.210872. Epub 2013 Jan 18. PMID: 23335624; PMCID: PMC3585581. [here](https://doi.org/10.1104/pp.112.210872)

51. Krouk G, Gojon A. *Un mécanisme original de perception d'un ion minéral (le nitrate): histoire de la découverte chez les plantes et perspectives [An original ion (nitrate) sensing mechanism: story of the discovery in plants and perspectives]*. **Med Sci (Paris).** 2011 Dec;27(12):1045-7. French. doi: 10.1051/medsci/20112712002. Epub 2011 Dec 23. PMID: 22192735. [here](https://doi.org/10.1051/medsci/20112712002)

52. Ruffel S, Krouk G, Ristova D, Shasha D, Birnbaum KD, Coruzzi GM. *Nitrogen economics of root foraging: transitive closure of the nitrate-cytokinin relay and distinct systemic signaling for N supply vs*. **demand.** Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18524-9. doi: 10.1073/pnas.1108684108. Epub 2011 Oct 24. PMID: 22025711; PMCID: PMC3215050. [here](https://doi.org/10.1073/pnas.1108684108)

53. Ravet K, Reyt G, Arnaud N, Krouk G, Djouani el-B, Boucherez J, Briat JF, Gaymard F. *Iron and ROS control of the DownSTream mRNA decay pathway is essential for plant fitness*. **EMBO J.** 2012 Jan 4;31(1):175-86. doi: 10.1038/emboj.2011.341. Epub 2011 Sep 23. PMID: 21946558; PMCID: PMC3252566. [here](https://doi.org/10.1038/emboj.2011.341)

54. Widiez T, El Kafafi el S, Girin T, Berr A, Ruffel S, Krouk G, Vayssières A, Shen WH, Coruzzi GM, Gojon A, Lepetit M. *High nitrogen insensitive 9 (HNI9)-mediated systemic repression of root NO3- uptake is associated with changes in histone methylation*. **Proc Natl Acad Sci U S A.** 2011 Aug 9;108(32):13329-34. doi: 10.1073/pnas.1017863108. Epub 2011 Jul 25. PMID: 21788519; PMCID: PMC3156160. [here](https://doi.org/10.1073/pnas.1017863108)

55. Krouk G, Ruffel S, Gutiérrez RA, Gojon A, Crawford NM, Coruzzi GM, Lacombe B. *A framework integrating plant growth with hormones and nutrients*. **Trends Plant Sci.** 2011 Apr;16(4):178-82. doi: 10.1016/j.tplants.2011.02.004. Epub 2011 Mar 9. PMID: 21393048. [here](https://doi.org/10.1016/j.tplants.2011.02.004)

56. Gojon A, Krouk G, Perrine-Walker F, Laugier E. *Nitrate transceptor(s) in plants*. **J Exp Bot.** 2011 Apr;62(7):2299-308. doi: 10.1093/jxb/erq419. Epub 2011 Jan 14. PMID: 21239382. [here](https://doi.org/10.1093/jxb/erq419)

57. Krouk G, Mirowski P, LeCun Y, Shasha DE, Coruzzi GM. *Predictive network modeling of the high-resolution dynamic plant transcriptome in response to nitrate*. **Genome Biol.** 2010;11(12):R123. doi: 10.1186/gb-2010-11-12-r123. Epub 2010 Dec 23. PMID: 21182762; PMCID: PMC3046483. [here](https://doi.org/10.1186/gb-2010-11-12-r123)

58. Obertello M, Krouk G, Katari MS, Runko SJ, Coruzzi GM. *Modeling the global effect of the basic-leucine zipper transcription factor 1 (bZIP1) on nitrogen and light regulation in Arabidopsis*. **BMC Syst Biol.** 2010 Aug 12;4:111. doi: 10.1186/1752-0509-4-111. PMID: 20704717; PMCID: PMC2933594. [here](https://doi.org/10.1186/1752-0509-4-111)

59. Krouk G, Lacombe B, Bielach A, Perrine-Walker F, Malinska K, Mounier E, Hoyerova K, Tillard P, Leon S, Ljung K, Zazimalova E, Benkova E, Nacry P, Gojon A. *Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants*. **Dev Cell.** 2010 Jun 15;18(6):927-37. doi: 10.1016/j.devcel.2010.05.008. PMID: 20627075. [here](https://doi.org/10.1016/j.devcel.2010.05.008)

60. Krouk G, Crawford NM, Coruzzi GM, Tsay YF. *Nitrate signaling: adaptation to fluctuating environments*. **Curr Opin Plant Biol.** 2010 Jun;13(3):266-73. doi: 10.1016/j.pbi.2009.12.003. Epub 2010 Jan 21. PMID: 20093067. [here](https://doi.org/10.1016/j.pbi.2009.12.003)

61. Ruffel S, Krouk G, Coruzzi GM. *A systems view of responses to nutritional cues in Arabidopsis: toward a paradigm shift for predictive network modeling*. **Plant Physiol.** 2010 Feb;152(2):445-52. doi: 10.1104/pp.109.148502. Epub 2009 Nov 25. PMID: 19939945; PMCID: PMC2815908. [here](https://doi.org/10.1104/pp.109.148502)

62. Nero D, Krouk G, Tranchina D, Coruzzi GM. *A system biology approach highlights a hormonal enhancer effect on regulation of genes in a nitrate responsive "biomodule"*. **BMC Syst Biol.** 2009 Jun 6;3:59. doi: 10.1186/1752-0509-3-59. PMID: 19500399; PMCID: PMC2702358. [here](https://doi.org/10.1186/1752-0509-3-59)

63. Krouk G, Tranchina D, Lejay L, Cruikshank AA, Shasha D, Coruzzi GM, Gutiérrez RA. *A systems approach uncovers restrictions for signal interactions regulating genome-wide responses to nutritional cues in Arabidopsis*. **PLoS Comput Biol.** 2009 Mar;5(3):e1000326. doi: 10.1371/journal.pcbi.1000326. Epub 2009 Mar 20. PMID: 19300494; PMCID: PMC2652106. [here](https://doi.org/10.1371/journal.pcbi.1000326)

64. Krouk G, Tillard P, Gojon A. *Regulation of the high-affinity NO3- uptake system by NRT1.1-mediated NO3- demand signaling in Arabidopsis*. **Plant Physiol.** 2006 Nov;142(3):1075-86. doi: 10.1104/pp.106.087510. Epub 2006 Sep 22. PMID: 16998085; PMCID: PMC1630733. [here](https://doi.org/10.1104/pp.106.087510)